Derek Xiao

Principal

Derek Xiao

AI SaaS Infrastructure Bio + Healthcare

As a Principal at Menlo Ventures, Derek focuses on early-stage investments across AI, cloud infrastructure, and digital health. He partners with companies from seed through inflection, including Anthropic, Eve, Neon, and Unstructured.

Derek joined Menlo from Bain & Company, where he advised technology investors on opportunities ranging from machine learning infrastructure to orbital launch. He graduated summa cum laude and Phi Beta Kappa from Harvard, and served as President of The Harvard Crimson while on campus. His passion for media led him to begin his career as a journalist at Forbes.

Today, Derek is the author of Menlo’s widely-cited AI research, including the firm’s flagship State of Enterprise AI reports. Outside of work, he enjoys playing with cameras, drones, and following the latest commentary on the future of news on Twitter (X): @derekgxiao.

Supported by: Nicole Sekeres, [email protected]

Investment Portfolio

Anthropic
Anthropic is an AI safety and research company that builds reliable, interpretable, and steerable AI systems.

Milestones

  • 2021 - Founded
  • 2023 - Partnered, Series C

Leadership

Dario Amodei
Co-Founder & CEO
Daniela Amodei
Co-Founder & President
Cartwheel
Cartwheel is a tech-enabled provider for youth mental health services, helping schools and families tackle the student mental health crisis.

Milestones

  • 2022 - Founded
  • 2023 - Partnered, Series A

Leadership

Joe English
Co-Founder & CEO
Daniel Tartakovsky
Co-Founder & COO

Partners

Eve
Eve is the industry’s first personalized AI assistant for the legal industry.

Milestones

  • 2020 - Founded
  • 2022 - Partnered, Seed

Leadership

Jay Madheswaran
Founder & CEO

Partners

Graphite
Graphite is an AI-powered developer productivity platform that helps developers create, review, and merge smaller code changes, stay unblocked, and ship faster.

Milestones

  • 2020 - Founded
  • 2025 - Partnered, Series B

Leadership

Merrill Lutsky
CEO & Co-Founder
Tomas Reimers
CPO & Co-Founder
Greg Foster
CTO & Co-Founder

Partners

Mercor
Mercor is an AI-powered hiring platform that matches talent with the opportunities they’re best suited for.

Milestones

  • 2023 - Founded
  • 2024 - Partnered, Series B

Leadership

Brendan Foody
CEO
Surya Midha
COO
Adarsh Hiremath
CTO
Neon
Neon is a multi-cloud Serverless Postgres provider that is purpose-built to address modern workloads oriented around edge computing and AI.

Milestones

  • 2021 - Founded
  • 2023 - Partnered, Series B
  • 2025 - Acquired by Databricks

Leadership

Nikita Shamgunov
Co-Founder & CEO
Heikki Linnakangas
Co-Founder
Stas Kelvich
Co-Founder

Partners

Typeface
Typeface is an enterprise-grade generative AI app to create engaging, personalized content faster and easier than ever before.

Milestones

  • 2022 - Founded
  • 2023 - Partnered, Series A

Leadership

Abhay Parasnis
Founder & CEO

Partners

Unstructured
Unstructured transforms organizations’ complex, unstructured data like PDFs, PPTX, HTML files, and more into formats compatible with LLMs so employees can chat with their internal data.

Milestones

  • 2022 - Founded
  • 2024 - Partnered, Series B

Leadership

Brian Raymond
Founder & CEO

Partners

Anthropic

Anthropic is an AI safety and research company that builds reliable, interpretable, and steerable AI systems.
Anthropic is an AI safety and research company that builds reliable, interpretable, and steerable AI systems.

Milestones

  • 2021 - Founded
  • 2023 - Partnered, Series C

Leadership

Dario Amodei
Co-Founder & CEO
Daniela Amodei
Co-Founder & President

Cartwheel

Cartwheel is a tech-enabled provider for youth mental health services, helping schools and families tackle the student mental health crisis.
Cartwheel is a tech-enabled provider for youth mental health services, helping schools and families tackle the student mental health crisis.

Milestones

  • 2022 - Founded
  • 2023 - Partnered, Series A

Leadership

Joe English
Co-Founder & CEO
Daniel Tartakovsky
Co-Founder & COO

Partners

Eleos Health

Eleos Health leverages specialized clinical AI models to turn behavioral health conversations into documentation and care intelligence, reducing admin work by over 50% and improving outcomes 3–4x.
Eleos Health leverages specialized clinical AI models to turn behavioral health conversations into documentation and care intelligence, reducing admin work by over 50% and improving outcomes 3–4x.

Milestones

  • 2020 - Founded
  • 2023 - Partnered, Series B

Leadership

Alon Joffe
Co-Founder & CEO
Dror Zaide
Co-Founder & COO
Alon Rabinovich
Co-Founder & CTO

Eve

Eve is the industry’s first personalized AI assistant for the legal industry.
Eve is the industry’s first personalized AI assistant for the legal industry.

Milestones

  • 2020 - Founded
  • 2022 - Partnered, Seed

Leadership

Jay Madheswaran
Founder & CEO

Partners

Graphite

Graphite is an AI-powered developer productivity platform that helps developers create, review, and merge smaller code changes, stay unblocked, and ship faster.
Graphite is an AI-powered developer productivity platform that helps developers create, review, and merge smaller code changes, stay unblocked, and ship faster.

Milestones

  • 2020 - Founded
  • 2025 - Partnered, Series B

Leadership

Merrill Lutsky
CEO & Co-Founder
Tomas Reimers
CPO & Co-Founder
Greg Foster
CTO & Co-Founder

Partners

Higgsfield

Higgsfield is a video AI company dedicated to democratizing social media content creation to everyone.
Higgsfield is a video AI company dedicated to democratizing social media content creation to everyone.

Milestones

  • 2023 - Founded
  • 2024 - Partnered, Seed

Leadership

Alexandr Mashrabov
Founder & CEO

Mercor

Mercor is an AI-powered hiring platform that matches talent with the opportunities they’re best suited for.
Mercor is an AI-powered hiring platform that matches talent with the opportunities they’re best suited for.

Milestones

  • 2023 - Founded
  • 2024 - Partnered, Series B

Leadership

Brendan Foody
CEO
Surya Midha
COO
Adarsh Hiremath
CTO

Neon

Neon is a multi-cloud Serverless Postgres provider that is purpose-built to address modern workloads oriented around edge computing and AI.
Acquired by Databricks
Neon is a multi-cloud Serverless Postgres provider that is purpose-built to address modern workloads oriented around edge computing and AI.

Milestones

  • 2021 - Founded
  • 2023 - Partnered, Series B
  • 2025 - Acquired by Databricks

Leadership

Nikita Shamgunov
Co-Founder & CEO
Heikki Linnakangas
Co-Founder
Stas Kelvich
Co-Founder

Partners

Obsidian Security

Obsidian aggregates, normalizes, and enriches user activity, access, and privilege data across SaaS applications to help organizations identify potential account compromise, data leakage, or insider threats.
Obsidian aggregates, normalizes, and enriches user activity, access, and privilege data across SaaS applications to help organizations identify potential account compromise, data leakage, or insider threats.

Milestones

  • 2017 - Founded
  • 2022 - Partnered, Series C

OfferFit

OfferFit is a ML-powered, automated experimentation platform for lifecycle marketers that enables true mass personalization on a 1:1 basis, all tailored to the specific goal of the marketers.
Acquired by Braze
OfferFit is a ML-powered, automated experimentation platform for lifecycle marketers that enables true mass personalization on a 1:1 basis, all tailored to the specific goal of the marketers.

Milestones

  • 2020 - Founded
  • 2023 - Partnered, Series B
  • 2025 - Acquired by Braze

Leadership

George Khachatryan
Co-Founder & CEO
Victor Kostyuk
Co-Founder & CTO

Partners

True Anomaly

True Anomaly is a deep technology company developing advanced hardware and software systems to ensure the sustainable security of space.
True Anomaly is a deep technology company developing advanced hardware and software systems to ensure the sustainable security of space.

Milestones

  • 2022 - Founded
  • 2023 - Partnered, Series B

Leadership

Even Rogers
Co-Founder & CEO
Tom Nichols
Co-Founder & CPO
Kyle Zakrzewski
Co-Founder & Chief Engineer

Partners

Typeface

Typeface is an enterprise-grade generative AI app to create engaging, personalized content faster and easier than ever before.
Typeface is an enterprise-grade generative AI app to create engaging, personalized content faster and easier than ever before.

Milestones

  • 2022 - Founded
  • 2023 - Partnered, Series A

Leadership

Abhay Parasnis
Founder & CEO

Partners

Unstructured

Unstructured transforms organizations’ complex, unstructured data like PDFs, PPTX, HTML files, and more into formats compatible with LLMs so employees can chat with their internal data.
Unstructured transforms organizations’ complex, unstructured data like PDFs, PPTX, HTML files, and more into formats compatible with LLMs so employees can chat with their internal data.

Milestones

  • 2022 - Founded
  • 2024 - Partnered, Series B

Leadership

Brian Raymond
Founder & CEO

Partners