

H. DuBose Montgomery
Founder & Partner EmeritusDuBose was a founder of Menlo Ventures in 1976 and, for almost 40 years, led many of Menlo’s investments in the medical and information technology sectors. His prior investments include: Asthmatx, acquired by Boston Scientific (BSX); EndoVascular Technologies, acquired by Johnson & Johnson (JNJ); Entone Technologies, acquired by Amino Technologies (AMO); Frame Technology Corporation, acquired by Adobe Systems (ADBE); Freightquote, acquired by C.H. Robinson (CHRW), Gilead Sciences (GILD); Infoseek Corporation, acquired by the Walt Disney Co. (DIS); LSI Logic Corporation(LSI), acquired by Broadcom (AVGO); Valid Logic Systems, acquired by Cadence Design Systems (CDNS) and VNUS Medical Technologies (VNUS), acquired by Covidien (COV).
DuBose is a graduate of the Massachusetts Institute of Technology (bachelor of science in electrical engineering, master of science in electrical engineering; bachelor of science in management science) and the Harvard University Graduate School of Business Administration (MBA with distinction). He previously served as a trustee of the MIT Corporation and on the MIT Visiting Committees for the Department of Electrical Engineering and Computer Science and for Sponsored Research. He also served as vice chairman of the Menlo School Board of Trustees in Atherton.
DuBose founded Menlo Ventures when he was 27 years old. He grew up in a small rural town in South Carolina and somehow found his way to Boston to go to school at MIT and HBS. Prior to founding Menlo, he also did research at Bell Labs in Murray Hill, NJ, and so a favorite book of his is The Idea Factory: Bell Labs and the Great Age of American Innovation. He is an inventor on two issued patents and has been published in the Proceedings of the IEEE.
DuBose helped found four successful startups from their initial idea concepts, incorporating them and providing the only investment in their seed-stage financing. Their subsequent combined market value exceeds $100 billion.
DuBose was a founder of Menlo Ventures in 1976 and, for almost 40 years, led many of Menlo’s investments in the medical and information technology sectors. His prior investments include: Asthmatx, acquired by Boston Scientific (BSX); EndoVascular Technologies, acquired by Johnson & Johnson (JNJ); Entone Technologies, acquired by Amino Technologies (AMO); Frame Technology Corporation, acquired by Adobe Systems (ADBE); Freightquote, acquired by C.H. Robinson (CHRW), Gilead Sciences (GILD); Infoseek Corporation, acquired by the Walt Disney Co. (DIS); LSI Logic Corporation(LSI), acquired by Broadcom (AVGO); Valid Logic Systems, acquired by Cadence Design Systems (CDNS) and VNUS Medical Technologies (VNUS), acquired by Covidien (COV).
DuBose is a graduate of the Massachusetts Institute of Technology (bachelor of science in electrical engineering, master of science in electrical engineering; bachelor of science in management science) and the Harvard University Graduate School of Business Administration (MBA with distinction). He previously served as a trustee of the MIT Corporation and on the MIT Visiting Committees for the Department of Electrical Engineering and Computer Science and for Sponsored Research. He also served as vice chairman of the Menlo School Board of Trustees in Atherton.
DuBose founded Menlo Ventures when he was 27 years old. He grew up in a small rural town in South Carolina and somehow found his way to Boston to go to school at MIT and HBS. Prior to founding Menlo, he also did research at Bell Labs in Murray Hill, NJ, and so a favorite book of his is The Idea Factory: Bell Labs and the Great Age of American Innovation. He is an inventor on two issued patents and has been published in the Proceedings of the IEEE.
DuBose helped found four successful startups from their initial idea concepts, incorporating them and providing the only investment in their seed-stage financing. Their subsequent combined market value exceeds $100 billion.
Investments
Our Portfolio

Entone was a provider of hybrid TV and media hub solutions that integrated broadcast television, DVR, web media services, and personal media sharing.
Milestones
- 1999 → Founded
- 2003 → Partnered, Series A
- 2015 → Acquired by Amino Technologies
Partner



Gilead is a research-based biopharmaceutical company that discovers, develops, and commercializes innovative medicines in areas of unmet medical need.
Milestones
- 1987 → Founded
- 1987 → Incubated by Menlo Ventures
- 1992 → IPO; NASDAQ: GILD
Partner



Infoseek was a popular search engine that pioneered marketing advertisements on its site and developed behavioral targeting algorithms.
Milestones
- 1994 → Founded
- 1998 → Partnered
- 1999 → Acquired by Disney
Partner



LSI Corporation designed semiconductors and software that accelerated storage and networking in data centers, mobile networks, and client computing.
Milestones
- 1981 → Founded
- 2014 → Acquired
Partner

Asthmatx was a medical device company focused on helping patients breathe easier. The company developed a catheter-based outpatient procedure that provided long-lasting and improved asthma control for adult severe asthma patients.
Milestones
- 2010 → Acquired
Partner
EndoVascular Technologies designed, developed, and manufactured minimally invasive endovascular systems to repair diseased or damaged vascular structures.
Milestones
- 1989 → Founded
- 1997 → Acquired by Guidant
Partner
Entone was a provider of hybrid TV and media hub solutions that integrated broadcast television, DVR, web media services, and personal media sharing.
Milestones
- 1999 → Founded
- 2003 → Partnered, Series A
- 2015 → Acquired by Amino Technologies
Partner


Frame Technology Corporation was the original developer of the FrameMaker document processor.
Milestones
- 1986 → Founded
- 1995 → Acquired
Partner
Freightquote is an online transportation broker of freight services throughout North America, providing shipping rates for national and regional freight carriers.
Milestones
- 1998 → Founded
- 2015 → Acquired by C.H. Robinson
Partner
Gilead is a research-based biopharmaceutical company that discovers, develops, and commercializes innovative medicines in areas of unmet medical need.
Milestones
- 1987 → Founded
- 1987 → Incubated by Menlo Ventures
- 1992 → IPO; NASDAQ: GILD
Partner


Infoseek was a popular search engine that pioneered marketing advertisements on its site and developed behavioral targeting algorithms.
Milestones
- 1994 → Founded
- 1998 → Partnered
- 1999 → Acquired by Disney
Partner


LSI Corporation designed semiconductors and software that accelerated storage and networking in data centers, mobile networks, and client computing.
Milestones
- 1981 → Founded
- 2014 → Acquired
Partner


Valid Logic Systems was a technology company that manufactured and distributed commercial electronic design automation systems.
Milestones
- 1989 → Acquired by Cadence Design Systems
Partner
VNUS Medical Technologies, Inc. developed, manufactured, and marketed the closure system used in the treatment of venous reflux disease.
Milestones
- 2004 → IPO; NASDAQ: VNUS